Journal of One Health Research

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2023-05-05T13:42:33+03:00

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Diagnostic Role of Bronchoscopy guided Endobronchial Needle Aspiration cytology Exophytic endobronchial lesions: A single-center study in a tertiary care setting in India

2022-12-11T15:24:52+03:00

Objective: In present study, various conventional diagnostic techniques (CDTs) such as endobronchial forcep biopsy (FB), bronchial washing (BW) and endobronchial needle aspiration cytology (EBNA) are employed during fiber-optic bronchoscopy for diagnosis of exophytic endobronchial lesions (EEL) and special emphasis is given to EBNA.
Material and method: Prospective, observational study, screened 1280 cases with suspected lung malignancy on clinical and radiological basis. Bronchoscopy guided techniques such as EBNA, BW, FB is used in exophytic endobronchial lesions (EEL) in confirming the diagnosis of lung cancer and to find additive yield over other techniques such as BW and FB. Rapid on-site evaluation (ROSE) analysis of all EBNA samples done in pathology lab allied center. Finally, histopathology proven 810 lung malignancy cases are included in study. Statistical analysis is done by using chi-test.
Results: In present study, 810 diagnosed lung cancer patients between 29-85 age group predominant males 59.25% (480/810) and smokers by addiction in 63.20% (512/810) cases. Presented with cough in 82.09% (665/810), clubbing in 56.17% (455/810) cases & mass lesion in chest radiograph in 42.22% (342/810) cases. Anatomical location is documented on right side of tracheobronchial in 59.01% (478/810) cases during bronchoscopy. Yield of forcep biopsy & forcep biopsy plus bronchial wash in EEL is 89.25% (723/810) & 93.08
% (754/810) respectively. Yield of EBNA, EBNA plus bronchial wash & EBNA plus forcep biopsy in EEL is 64.56% (523/810), 67.28% (545/810) & 97.65% (791/810) respectively. Total yield of all fiberoptic bronchoscopy guided procedures (EBNA+FB+BW) in EEL is 100%. Additional yield of EBNA in EEL over other CDTs is 6.92%. Sensitivity of forcep biopsy & EBNA in diagnosing lung malignancy in EEL is 89.25% & 64.56% respectively. Forcep biopsy is more sensitive technique than EBNA in EEL. (p <0.00001). Sensitivity of forcep biopsy plus bronchial wash in EEL is 93.08% (754/810). Sensitivity of EBNA plus bronchial wash in EEL is 67.28% (545/810).Sensitivity of EBNA plus forcep biopsy in EEL is 97.65% (791/810) (p<0.00001)
Conclusion: Endobronchial needle aspiration has documented very crucial role in diagnosing lung cancer in comparison to other conventional diagnostic techniques. Although Forcep biopsy is more sensitive test then EBNA in EEL in diagnosing disease, we have documented EBNA has significant additive yield in proportionate number of cases. EBNA is safe, sensitive and cytology samples can give comparable results to histopathology.

OBEZ BİREYLERDE DİYABETİN GECE YEME SENDROMU İLE İLİŞKİSİNİN DEĞERLENDİRİLMESİ

2023-03-28T13:51:15+03:00

Objective: The aim of this study was to investigate the relationship between diabetes and night eating syndrome in obese individuals.

Material and method: This cross sectional study was conducted with 113 (94 female, 19 male) obese individuals between 01.10.2018 and 31.10.2018. Measurements of body weight and height of individuals were made according to the anthropometric measurement technique. Socio-demographic data form was applied by face-to-face survey method. The diagnostic criteria for nighttime eating disorder, which has been validated in Turkish, were used in the evaluation of night eating syndrome.

Results: It was seen that the mean for nighttime eating disorder scale of the group with diabetes was 24,68±8,60 and the mean for nighttime eating disorder scale score of the non-diabetic group was 24,25±10,46 (p=0,112). On the other hand according to body weight there was a significant difference between two group according to presence of night eating syndrome (p=0,112).

Conclusion: It was found that the presence of night eating syndrome do not differ according to diabetes, but body weight.

Evaluation of driver’s license health reports prepared at Kartal Dr.Lütfi Kırdar City Hospital Educational Family Health Centers

2023-02-18T21:02:28+03:00

Objective: With the ‘’Regulation on the health conditions and examinations to be sought in driver candidates and drivers’’, which was published in the Official Gazette 26.09.2006 and numbered 26301, doctors and specialist doctors working in Family Health Centers (FHC) were authorized to issue driving licences health report (DLHR). While issuing this document, it is necessary tocomply with the health conditions and inspection principles specified in the regulation. Health reports have an important place among the daily workload of physicians working in Family Health Centers (FHCs). The aim of this study is to determine the characteristics of the people who are given a driver’s health report and to reveal the problems that may be encountered in the reporting processes and the points to be considered.

Material and method: Driver health reports prepared in Kartal Dr.Lütfi Kırdar City Hospital E-FHCs in the years 2020-2022 were reviewed retrospectively. The sociodemographic and health characteristics of 300 people who were given a driver’s health report were determined. Data were analyzed with SPSS 17 (Statistical Package for the Social Sciences - IBM^®) program.

Results: 55% (n=165) of the participants were female and 45%(n=135) were male. The mean age is 35.9±12.2 years.66.7%(n=200) of the participants are universary graduates. 18.0%(n=54) of the participants had a limitation. There was no significant difference between the disability status and gender, year of application and education level. While 49.3%(n=148) of the participants applied for a license for the first time,50.7%(n=152) applied for renewal.18.0% (n=54) of the participants had an additional disease; 3.3%(n=10) had diabetes and 5.0% (n=15) had hypertension. 13.0% (n=39) of the participants had an additional disease other than diabetes and hypertension.

Conclusion: Additional diseases, drug use status and limitations of the participants applying for a driver’s license health report should be screened, the driver’s health reports should be prepared in accordance with the regulation, and they should be referred to an additional branch or higher level health institutions when necessary.

Dogo Argentino Irkı Bir Köpekte Görülen Viseral Leishmaniasisin Patolojik Bulguları

2023-05-02T15:00:14+03:00

A six-year-old, Dogo Argentino male dog, which had been treated for Leishmaniasis for 6 months, was brought to Burdur Mehmet Akif Ersoy University Veterinary Faculty clinics with complaints of partial paralysis, vomiting, lethargy, anorexia and deterioration in general condition. Due to the death of the dog during the treatment, it was sent to the Department of Pathology for necropsy. Macroscopically; The liver and spleen was enlarged and had a granular surface. In the kidney, uroliths were found in the calyx renalis. Microscopically, multifocal granulomatous hepatitis, splenitis, focal myelitis and multifocal nonsuppurative glomerulonephritis were observed.; Leishmania spp. were detected cytoplasm of macrophages in the liver kidney,spleen and medulla spinalis with Giemsa staining. Biochemical analyzes of urolites were determined to be of xanthine origin. In this study, a case of visceral Leishmaniasis associated with Xanthine Urolithiasis in a Dogo argentino dog was examined with its clinical, macroscopic and microscopical findings in detail.